In the study of januvia as add-on combination therapy with metformin and rosiglitazone table 1 , through week 54 the adverse reactions reported regardless of investigator assessment of causality in 5 of patients treated with januvia and more commonly than in patients treated with placebo were upper respiratory tract infection januvia, 15.
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an overdose of metformin and glimepiride can lead to lactic acidosis.
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once again, however, the incidence was not statistically different from the incidence in patients not taking metformin 28 per 100,000 patient-years; p .
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lactic acidosis associated with metformin is rare and has occurred mostly in people whose kidneys were not working normally.
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impaired hepatic function since impaired hepatic function has been associated with some cases of lactic acidosis, glycomet gp metformin hydrochloride hydrochloride tablets should generally be avoided in patients with clinical or laboratory evidence of hepatic disease.
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after a few months of taking januvia along with metformin they rose.
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