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since chloramphenicol is metabolized in the liver, it should be used only with careful monitoring in horses with liver or kidney problems.

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blood dyscrasias, including aplastic anaemia, may be associated with the use of chloramphenicol.

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10 15 high rates of resistance to second-line antibiotics such as chloramphenicol, gentamicin and cephalosporins have also been reported in selected contexts, 12 15 while in general, sensitivity to ciprofloxacin remains high table 1 .

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